PE/XFD610 Anti-human CD30 Antibody *MEM-268*

Catalogue Number: 103001P1-AAT

Manufacturer:AAT Bioquest
Shelf Life:12 months
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 100 tests
Host name: Mouse
Clone: MEM-268
Isotype: IgG
Immunogen:

Description

Description: MEM-268 is an anti-human monoclonal antibody that recognizes the CD30 antigen. CD30 (also known as Ber-H2, TNFRSF8 or Ki-1) is a 64 kD transmembrane protein that is located on the surface of cells like T cells and macrophages. In many organisms, CD30 promotes apoptotic process, is a suppressor of cell population proliferation and is an enhancer of TRAIL biosynthetic process. Additionally, it is a component of important cellular pathways, for instance, the tumor necrosis factor-mediated signaling pathway. From a research standpoint, it is of biological interest due to its association with essential macromolecules/ligands such as CD153. CD30 is a fairly uncommon antibody target, with a little more than 6900 publications in the last decade. Even still, CD30 is commonly used in flow cytometry applications as a phenotypic marker for differentiation of cell types, particularly in the study of stem cells and immunology. This antibody was purified through affinity chromatography and conjugated to PE/XFD610 (ex/em = 567/627 nm). XFD610 is manufactured by AAT Bioquest, and it has the same chemical structure of Alexa Fluor® 610 (Alexa Fluor® is the trademark of ThermoFisher). It is compatible with the 561 nm laser and 610/20 nm bandpass filter (for example, as in the BD LSRFortessa™ X-20).

Additional Text

Antibody Clonality

Monoclonal

Storage Note

See Protocol|12 months