Anti-Human ORP150 (Oxygen Regulated Protein, p150) (2F07) MouseIgG MoAb 10301
Catalogue Number: 10301-IBL
| Manufacturer: | IBL - (Immuno-Biologicals Laboratories Co Ltd) |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Storage Condition: | 2-8°C |
| Unit(s): | 100 ug, 10 ug |
| Host name: | Mouse |
| Clone: | |
| Isotype: | IgG, IgG2a |
| Immunogen: | Recombinant Protein ORP150 (Leu 508 - Leu 999) |
| Application: | IP, WB, IHC |
Description
Description: Heat shock proteins (HSPs)/stress proteins are molecular chaperones that are induced by various environmental and physiological stimuli. The 150-kDa oxygen-regulated protein (ORP150), a new member of HSP family, functions as a molecular chaperone in the endoplasmic reticulum (1). It is reported that the ORP150 is an integral participant in ischemic cytoprotective pathways. (2). And, the ORP150 is expressed in human wounds along with VEGF. Colocalization of these two molecules was observed in macrophages in the neovasculature, suggesting a role of ORP150 in the promotion of angiogenesis (3). Furthermore, ORP150 is up-regulated in tumors and, in breast tumors, may be associated with tumor invasiveness.
Additional Text
Purification
Protein A purified
Antibody Clonality
Monoclonal
10301 Datasheet
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