Anti-Human ORP150 (Oxygen Regulated Protein, p150) (2F07) Mouse IgG MoAb

Catalogue Number: 10301-IBL

Manufacturer:IBL - (Immuno-Biologicals Laboratories Co Ltd)
Type:Monoclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Storage Condition:2-8°C
Unit(s): 100 ug, 10 ug
Host name: Mouse
Clone: 2F07
Isotype: IgG, IgG2a
Immunogen: Recombinant Protein ORP150 (Leu 508 - Leu 999)
Application: IP, WB, IHC

Description

Description: Heat shock proteins (HSPs)/stress proteins are molecular chaperones that are induced by various environmental and physiological stimuli. The 150-kDa oxygen-regulated protein (ORP150), a new member of HSP family, functions as a molecular chaperone in the endoplasmic reticulum (1). It is reported that the ORP150 is an integral participant in ischemic cytoprotective pathways. (2). And, the ORP150 is expressed in human wounds along with VEGF. Colocalization of these two molecules was observed in macrophages in the neovasculature, suggesting a role of ORP150 in the promotion of angiogenesis (3). Furthermore, ORP150 is up-regulated in tumors and, in breast tumors, may be associated with tumor invasiveness.

Price
280.00


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