Catalogue Number: 10320121-AAT
| Manufacturer: | AAT Bioquest |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 500 tests |
| Host name: | Mouse |
| Clone: | IV.3 |
| Isotype: | IgG2b |
| Immunogen: | |
| Application: | FC, IF |
Description: IV.3 is an anti-human monoclonal antibody that forms an immune complex with the CD32 antigen. CD32 (sometimes referred to as FCGR2A or FcγRII) is a 40 kD single-pass type I membrane protein that is expressed on the surface of cells such as . CD32 plays a role in essential cellular pathways, namely, the Fc-gamma receptor signaling pathway involved in phagocytosis. From a research standpoint, it is of biological interest due to its association with important macromolecules/ligands like . CD32 is a fairly uncommon antibody target, with a little more than 7000 publications in the last decade. Even still, CD32 is frequently used in flow cytometry applications as a phenotypic marker for differentiation of cell types, particularly in the study of immunology and innate immunity. This antibody was purified through affinity chromatography and conjugated to mFluor™ Violet 540 (ex/em = 394/537 nm). It is compatible with the 405 nm laser and 525/40 nm bandpass filter (for example, as in the Beckman Coulter DxFLEX).
Monoclonal
See Protocol|12 months