PE/Cy5 Anti-human CD32 Antibody *IV.3*

Catalogue Number: 103201M0-AAT

Manufacturer:AAT Bioquest
Shelf Life:12 months
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 25 tests
Host name: Mouse
Clone: IV.3
Isotype: IgG2b
Immunogen:

Description

Description: IV.3 is an anti-human monoclonal antibody that forms an immune complex with the CD32 antigen. CD32 (sometimes referred to as FCGR2A or FcγRII) is a 40 kD single-pass type I membrane protein that is expressed on the surface of cells such as . CD32 plays a role in essential cellular pathways, namely, the Fc-gamma receptor signaling pathway involved in phagocytosis. From a research standpoint, it is of biological interest due to its association with important macromolecules/ligands like . CD32 is a fairly uncommon antibody target, with a little more than 7000 publications in the last decade. Even still, CD32 is frequently used in flow cytometry applications as a phenotypic marker for differentiation of cell types, particularly in the study of immunology and innate immunity. This antibody was purified through affinity chromatography and conjugated to PE/Cy5 (ex/em = 565/666 nm). It is compatible with the 561 nm laser and 670/30 nm bandpass filter (for example, as in the BD Special Order LSRFortessa™ Cell Analyzer).

Additional Text

Antibody Clonality

Monoclonal

Storage Note

See Protocol|12 months