XFD700 Anti-human CD32 Antibody *3D3*

Catalogue Number: 103211A1-AAT

Manufacturer:AAT Bioquest
Shelf Life:12 months
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 500 tests
Host name: Mouse
Clone: 3D3
Isotype: IgG1, kappa
Immunogen:
Application: FC, IF

Description

Description: The 3D3 monoclonal antibody binds to human CD32, a 40 kD member of the Ig superfamily often located on the surface of platelets, monocytes, B cells, granulocytes and dendritic cells. CD32 is involved with essential cellular pathways, namely, the Fc-gamma receptor signaling pathway involved in phagocytosis. From a research standpoint, it is of biological interest due to its association with essential macromolecules/ligands. CD32 is a fairly uncommon antibody target, with a little more than 7000 publications in the last decade. Even still, CD32 has been widely used in innate immunity and immunology research, often serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to XFD700 (ex/em = 696/719 nm). XFD700 is manufactured by AAT Bioquest, and it has the same chemical structure of Alexa Fluor® 700 (Alexa Fluor® is the trademark of ThermoFisher).

Additional Text

Antibody Clonality

Monoclonal

Storage Note

See Protocol|12 months