Purified Anti-human CD33 Antibody *HI33a*
Catalogue Number: 10330000-AAT
| Manufacturer: | AAT Bioquest |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Mouse |
| Clone: | HI33a |
| Isotype: | IgG2a |
| Immunogen: | |
| Application: | ELISA, FC, WB |
Description
Description: The HI33a monoclonal antibody recognizes human CD33, a 67 kD single-pass type i membrane protein frequently expressed on the surface of monocytes, neutrophils, dendritic cells and mast cells. In some organisms, CD33 plays a role in the downregulation of calcium ion transport, is a suppressor of tumor necrosis factor production and is an inhibitor of interleukin-1 beta production. Additionally, it has been closely linked to vital biological processes such as signal transduction, especially immune response-inhibiting signal transduction. From a research standpoint, it is of biological interest due to its association with important macromolecules/ligands such as ?-2 and 6- linked Sialic acid. CD33 is a fairly uncommon antibody target, with a little more than 8000 publications in the last decade. Even still, CD33 is typically used in flow cytometry applications as a phenotypic marker for differentiation of cell types, specifically in the study of neuroscience. This antibody was purified through affinity chromatography.
Additional Text
Antibody Clonality
Monoclonal
Storage Note
Refrigerated (2-8 °C); Minimize light exposure;|12 months
10330000 Protocol
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DELIVERY
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