iFluor® 680 Anti-human CD33 Antibody *HIM3-4*

Catalogue Number: 103310I0-AAT

Manufacturer:AAT Bioquest
Shelf Life:12 months
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 100 tests
Host name: Mouse
Clone: HIM3-4
Isotype: IgG1
Immunogen:
Application: FC, IF

Description

Description: HIM3-4 is an anti-human monoclonal antibody that forms an immune complex with the CD33 antigen. CD33 (sometimes referred to as p67) is a 67 kD transmembrane glycoprotein that is located on the surface of cells such as macrophages and granulocytes. CD33 has been thought to be involved with important biological processes like signal transduction, specifically immune response-inhibiting signal transduction. Also, in certain organisms, it is a promoter of protein secretion, is an enhancer of protein tyrosine phosphatase activity and is a repressor of interleukin-8 production. From a research standpoint, it is of biological interest due to its association with important macromolecules/ligands like ?-2, Sugar chains containing sialic acid and 6- linked Sialic acid. CD33 is a fairly uncommon antibody target, with a little more than 8000 publications in the last decade. Even still, CD33 is essential for immunology, neuroinflammation and cell biology research, commonly serving as a phenotypic marker for differentiating cell types in flow cytometric apl, Cat No. 103310J0We provide custom conjugation of iFluor® 700 Anti-human CD33 Antibody *HIM3-4* with common reporters such as HRP, Alexa Fluor® etc.

Additional Text

Antibody Clonality

Monoclonal

Storage Note

See Protocol|12 months