Anti-Human Tenascin-C (Domain B) (4C8MS) Mouse IgG MoAb

Catalogue Number: 10335-IBL

Manufacturer:IBL - (Immuno-Biologicals Laboratories Co Ltd)
Physical state:Lyophilized product from 1 % BSA in PBS containing 0.05 % NaN3
Type:Monoclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Storage Condition:2-8°C
Unit(s): 100 ug, 10 ug
Host name:
Clone: 4C8MS
Isotype: IgG1
Immunogen: Human Recombinant Tenascin-C

Description

Description: Tenascin-C (TN-C) is a component of the extracellular matrix (ECM) that has been shown to be involved in tissue interactions during fetal development and oncogenesis. It is glycoprotein consisting of six disulphide monomer isoforms being generated by alternative splicing. A high molecular weight variant that is generated by alternative splicing of RNAs of TN-C was found predominantly in breast, prostatic and colorectal cancers. The appearance of such a large TN-C isoform has been suggested to be of significance for tumour progression.

Additional Text

Specificity

Reacts with domain B in FNIII repeatsof Tenascin-C. Cross-reacts with mouse and rat

Price
280.00


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