mFluor™ Green 620 Anti-human CD34 Antibody *4H11*

Catalogue Number: 103400U1-AAT

Manufacturer:AAT Bioquest
Shelf Life:12 months
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 500 tests
Host name: Mouse
Clone: 4H11
Isotype: IgG1
Immunogen:
Application: FC, IF

Description

Description: 4H11 is an anti-human monoclonal antibody that recognizes the CD34 antigen. CD34 (sometimes called Gp105-120) is a 105 - 120 kD glycoprotein that is located on the surface of cells like endothelial cells and stem cells. In many organisms, CD34 plays a role in the downregulation of tumor necrosis factor production, positively regulates granulocyte colony-stimulating factor production and is involved in the positive regulation of vasculogenesis. Also, it has been associated with vital biological processes such as endothelium development, especially glomerular endothelium development. From a research standpoint, it is of biological interest due to its association with critical macromolecules/ligands like MadCAM-1, CRKL and L-Selectin. CD34 is a very popular antibody target, with over 55000 publications in the last decade. CD34 is vital to neuroscience, neuroinflammation and immunology research, typically serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to mFluor™ Green 620 (ex/em = 525/623 nm). It is compatible with the 532 nm laser and 610/20 nm bandpass filter (for example, as in the BD FACSymphony™ A5).

Additional Text

Antibody Clonality

Monoclonal

Storage Note

See Protocol|12 months