Catalogue Number: 10343-IBL
|Manufacturer:||IBL - (Immuno-Biologicals Laboratories Co Ltd)|
|Physical state:||Lyophilized product from 1 % BSA in PBS containing 0.05 % NaN3|
|Type:||Monoclonal Primary Antibody - Unconjugated|
|Shipping Condition:||Blue Ice|
|Unit(s):||100 ug, 10 ug|
|Immunogen:||Recombinant Rat mTOR|
Description: Rapamycin is a lipophilic macrolide compound and induces a G1 phase growth arrest in S. cerevisiae and mammalian cells. The mammalian target of rapamycin (mTOR) has a molecular weight of 290 kDa and a Ser/Thr protein kinase acivity. mTOR has been shown to be an upstream regulator of translational effectors, such as p70 S6 kinase and eIF4E- binding protein 1, and plays a crucial role in a nutrient-sensitive signalling pathway that regulates cell growth.
Reacts to rat and human mTOR. Both recombinant and native forms can be detected.