Anti-Rat Occludin (1A8) Mouse IgM MoAb

Catalogue Number: 10345-IBL

Manufacturer:IBL - (Immuno-Biologicals Laboratories Co Ltd)
Type:Monoclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Storage Condition:2-8°C
Unit(s): 50 ug, 5 ug
Host name:
Clone: 1A8
Isotype: IgM
Immunogen: Recombinant Rat Occludin
Application: WB, IHC


Description: Occludin is an approximately 60kDa-integral membrane protein localizing at Tight-Junction, and composed of short N-terminal cytosolic domain, four transmembrane domains and long C-terminal cytosolic domain. It is reported that Occludin has no homology to claudin family and forms strand by coporimerization with claudin family proteins. It is considered that Tight-Junction plays an important role in maintenance of cellular polarity (fence function) and in regulating the passage of ions and small molecular through the paracellular pathway (barrier function).


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