Catalogue Number: 10345-IBL
|Manufacturer:||IBL - (Immuno-Biologicals Laboratories Co Ltd)|
|Type:||Monoclonal Primary Antibody - Unconjugated|
|Shipping Condition:||Blue Ice|
|Unit(s):||50 ug, 5 ug|
|Immunogen:||Recombinant Rat Occludin|
Description: Occludin is an approximately 60kDa-integral membrane protein localizing at Tight-Junction, and composed of short N-terminal cytosolic domain, four transmembrane domains and long C-terminal cytosolic domain. It is reported that Occludin has no homology to claudin family and forms strand by coporimerization with claudin family proteins. It is considered that Tight-Junction plays an important role in maintenance of cellular polarity (fence function) and in regulating the passage of ions and small molecular through the paracellular pathway (barrier function).