Anti-Human c-Kit (12A8) Mouse IgG MoAb

Catalogue Number: 10349-IBL

Manufacturer:IBL - (Immuno-Biologicals Laboratories Co Ltd)
Type:Monoclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Storage Condition:2-8°C
Unit(s): 100 ug, 10 ug
Host name: Mouse
Clone: 12A8
Isotype: IgG, IgG1
Immunogen: Recombinant protein of extracellular domain of human c-Kit
Application: FC, IP, WB


Description: The proto-oncogene c-kit encodes a transmembrane tyrosine kinase receptor, and its ligand for c-Kit receptor has been identified as the stem cell factor (SCF). Recent experimental studies have shown that c-Kit plays a key role in the development of a component of the pacemaker system that is required for generation of autonomic gut motility. These studies further suggest that interaction of the c-Kit and SCF is essential for development of enteric nervous system. Recently, it is reported that the c-Kit may be an important marker for gastrointestinal stromal tumors (GISTs) which may originate from the interstitial cells of Cajal (ICCs).


Find out about delivery


outstanding technical support


we offer a full product guarantee


we offer free delivery to UK universities and non profit organisations