iFluor® 532 Anti-human CD38 Antibody *HI157*
Catalogue Number: 10381070-AAT
| Manufacturer: | AAT Bioquest |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 tests |
| Host name: | Mouse |
| Clone: | HI157 |
| Isotype: | IgG2a |
| Immunogen: | |
| Application: | FC, IF |
Description
Description: The HI157 monoclonal antibody binds to human CD38, a 45 kD transmembrane glycoprotein typically found on the surface of plasma cells, dendritic cells and myeloids. CD38 acts in important cellular pathways, in particular, the B cell receptor signaling pathway and apoptotic signaling pathway. Also, in many organisms, it acts to positively regulate vasoconstriction, acts to positively regulate cell growth and is a positive regulator of insulin secretion. From a research standpoint, it is of biological interest due to its association with essential macromolecules/ligands such as CD3/TcR complex, HLA Class II, Hyaluronic acid and CD31. CD38 is a fairly uncommon antibody target, with a little more than 10000 publications in the last decade. Even still, CD38 is often used in flow cytometry applications as a phenotypic marker for differentiation of cell types, specifically in the study of immunology. This antibody was purified through affinity chromatography and conjugated to iFluor® 532 (ex/em = 537/560 nm). It is compatible with the 532 nm laser and 575/25 nm bandpass filter (for example, as in the BD Special Order LSRFortessa™ Cell Analyzer).
Additional Text
Antibody Clonality
Monoclonal
Storage Note
See Protocol|12 months
10381070 Protocol
SUPPORT
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PRODUCT
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DELIVERY
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