XFD488 Anti-human CD38 Antibody *HB7*
Catalogue Number: 10382141-AAT
| Manufacturer: | AAT Bioquest |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 500 tests |
| Host name: | Mouse |
| Clone: | HB7 |
| Isotype: | IgG1, kappa |
| Immunogen: | |
| Application: | FC, IF |
Description
Description: HB7 is an anti-human monoclonal antibody that recognizes the CD38 antigen. CD38 (alternatively called ADP-ribosyl cyclase or T10) is a 45 kD transmembrane glycoprotein that is expressed on the surface of cells such as B cells, dendritic cells and macrophages. CD38 is a component of critical cellular pathways, for instance, the apoptotic signaling pathway and B cell receptor signaling pathway. In addition, in many organisms, it is a repressor of bone resorption, is involved in the positive regulation of cell growth and is involved in the positive regulation of vasoconstriction. From a research standpoint, it is of biological interest due to its association with essential macromolecules/ligands such as hyaluronic acid and CD16. CD38 is a moderately popular antibody target, with over 15000 publications in the last decade. CD38 is typically used in flow cytometry applications as a phenotypic marker for differentiation of cell types, specifically in the study of immunology. This antibody was purified through affinity chromatography and conjugated to XFD488 (ex/em = 499/520 nm). XFD488 is manufactured by AAT Bioquest, and it has the same chemical structure of Alexa Fluor® 488 (Alexa Fluor® is the trademark of ThermoFisher). It is compatible with the 488 nm laser and 530/30 nm bandpass filter (for example, as in the Agilent Technologies NovoCyte).
Additional Text
Antibody Clonality
Monoclonal
Storage Note
See Protocol|12 months
10382141 MSDS
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