PE/iFluor® 700 Anti-human CD40 Antibody *HI40a*

PE/iFluor® 700 Anti-human CD40 Antibody HI40a

Catalogue Number: 104001X1-AAT

Manufacturer:	AAT Bioquest
Shelf Life:	12 months
Type:	Monoclonal Primary Antibody - Conjugated
Shipping Condition:	Blue Ice
Unit(s):	100 tests
Host name:	Mouse
Clone:	HI40a
Isotype:	IgG2b
Immunogen:

Overview
Datasheets

Description

Description: HI40a is an anti-human monoclonal antibody that targets the CD40 antigen. CD40 (alternatively called TNFRSF5) is a 48 kD transmembrane protein that is found on the surface of cells such as dendritic cells and epithelial cells. CD40 is a member of important cellular pathways, for instance, the tumor necrosis factor-mediated signaling pathway, immune response-regulating cell surface receptor signaling pathway and CD40 signaling pathway. Also, in many organisms, it upregulates GTPase activity, is a promoter of protein kinase C signaling and promotes transcription by RNA polymerase II. From a research standpoint, it is of biological interest due to its association with key macromolecules/ligands like TRAP and CD154. CD40 is a very popular antibody target, with over 30000 publications in the last decade. CD40 is commonly used in flow cytometry applications as a phenotypic marker for differentiation of cell types, specifically in the study of cell biology and neuroscience. This antibody was purified through affinity chromatography and conjugated to PE/iFluor® 700 (ex/em = 566/708 nm). It is compatible with the 561 nm laser and 710/50 nm bandpass filter (for example, as in the BD FACSAria™ III).

Additional Text

Antibody Clonality

Monoclonal

Storage Note

See Protocol|12 months

104001X1 Protocol

104001X1 MSDS

Price

£641.00

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