iFluor® 647 Anti-human CD40 Antibody *G28.5*
Catalogue Number: 104010F0-AAT
| Manufacturer: | AAT Bioquest |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 tests |
| Host name: | Mouse |
| Clone: | G28.5 |
| Isotype: | IgG1, kappa |
| Immunogen: | |
| Application: | FC, IF |
Description
Description: G28.5 is an anti-human monoclonal antibody that targets the CD40 antigen. CD40 (also known as Bp50) is a 48 kD transmembrane protein that is expressed on the surface of cells like macrophages, dendritic cells and stem cells. CD40 is a component of key cellular pathways, in particular, the tumor necrosis factor-mediated signaling pathway, immune response-regulating cell surface receptor signaling pathway and CD40 signaling pathway. Also, in many organisms, it upregulates interleukin-12 production, is a positive regulator of isotype switching to IgG isotypes and is a promoter of protein phosphorylation. From a research standpoint, it is of biological interest due to its association with vital macromolecules/ligands like CD40L, CD154 and TRAP. CD40 is a very popular antibody target, with over 30000 publications in the last decade. CD40 is often used in flow cytometry applications as a phenotypic marker for differentiation of cell types, especially in the study of neuroscience. This antibody was purified through affinity chromatography and conjugated to iFluor® 647 (ex/em = 656/670 nm). It is compatible with the 640 nm laser and 670/30 nm bandpass filter (for example, as in the BD FACSAria™ Fusion).
Additional Text
Antibody Clonality
Monoclonal
Storage Note
See Protocol|12 months
104010F0 Protocol
SUPPORT
outstanding technical support
PRODUCT
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DELIVERY
we offer free delivery to UK universities and non profit organisations