Catalogue Number: 104110W0-AAT
| Manufacturer: | AAT Bioquest |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 tests |
| Host name: | Mouse |
| Clone: | HIP2 |
| Isotype: | IgG3 |
| Immunogen: | |
| Application: | FC, IF |
Description: The HIP2 monoclonal antibody binds to human CD41, a 22 kD glycoprotein frequently expressed on the surface of megakaryocytes and platelets. In certain organisms, CD41 is a promoter of leukocyte migration. Also, it acts in important cellular pathways, for example, the integrin-mediated signaling pathway. From a research standpoint, it is of biological interest due to its association with critical macromolecules/ligands such as von Willebrand factor (vWF), Fibrinogen and Fibronectin. CD41 is a fairly uncommon antibody target, with a little more than 4000 publications in the last decade. Even still, CD41 is vital to cell adhesion, immunology and cell biology research, frequently serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to mFluor™ Red 780 (ex/em = 629/767 nm). It is compatible with the 633 nm laser and 780/60 nm bandpass filter (for example, as in the BD FACSCelesta™).
Monoclonal
See Protocol|12 months