PacOrange Anti-human CD41 Antibody *HIP2*

Catalogue Number: 104111K1-AAT

Manufacturer:AAT Bioquest
Shelf Life:12 months
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 500 tests
Host name: Mouse
Clone: HIP2
Isotype: IgG3
Immunogen:
Application: FC, IF

Description

Description: The HIP2 monoclonal antibody binds to human CD41, a 22 kD glycoprotein frequently expressed on the surface of megakaryocytes and platelets. In certain organisms, CD41 is a promoter of leukocyte migration. Also, it acts in important cellular pathways, for example, the integrin-mediated signaling pathway. From a research standpoint, it is of biological interest due to its association with critical macromolecules/ligands such as von Willebrand factor (vWF), Fibrinogen and Fibronectin. CD41 is a fairly uncommon antibody target, with a little more than 4000 publications in the last decade. Even still, CD41 is vital to cell adhesion, immunology and cell biology research, frequently serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to PacOrange (ex/em = 400/551 nm). It is compatible with the 405 nm laser and 525/50 nm bandpass filter (for example, as in the Miltenyi Biotec MACSQuant X).

Additional Text

Antibody Clonality

Monoclonal

Storage Note

See Protocol|12 months