Anti-Human CD20 (N) (4-6H:2C) Mouse IgG MoAb

Catalogue Number: 10415-IBL

Manufacturer:IBL - (Immuno-Biologicals Laboratories Co Ltd)
Physical state:Lyophilized product from 1.0 mL of PBS containing 1 % BSA and 0.05 % NaN3
Type:Monoclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Storage Condition:2-8°C
Unit(s): 100 ug, 10 ug
Host name:
Clone: 4-6H:2C
Isotype: IgG3
Immunogen: Synthetic peptide of the N-terminal part of human CD20 (CMQSGPKPLFRRMSS)


Description: Rituximab used for treatment of lymphoma is an antibody drug of which target is pan-B cell marker, CD20. It has been reported that the C-terminal region of CD20 undertakes a critical role in a binding to rituximab and the association between C-terminal mutations and rituximab-resistance has been investigated. This antibody was developed as a new monoclonal antibody that recognizes the N-terminal region of CD20 molecule to detect comprehensive CD20 regardless of C-terminal mutations. It is expected to be useful for the detailed examination of CD20 molecules by adding this antibody to reserch of CD20.


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