Catalogue Number: 10415-IBL
Manufacturer: | IBL - (Immuno-Biologicals Laboratories Co Ltd) |
Type: | Monoclonal Primary Antibody - Unconjugated |
Shipping Condition: | Blue Ice |
Storage Condition: | 2-8°C |
Unit(s): | 100 ug, 10 ug |
Host name: | Mouse |
Clone: | 4-6H:2C |
Isotype: | IgG, IgG3 |
Immunogen: | Synthetic peptide of the N-terminal part of human CD20 (CMQSGPKPLFRRMSS) |
Application: | WB, IHC |
Description: Rituximab used for treatment of lymphoma is an antibody drug of which target is pan-B cell marker, CD20. It has been reported that the C-terminal region of CD20 undertakes a critical role in a binding to rituximab and the association between C-terminal mutations and rituximab-resistance has been investigated. This antibody was developed as a new monoclonal antibody that recognizes the N-terminal region of CD20 molecule to detect comprehensive CD20 regardless of C-terminal mutations. It is expected to be useful for the detailed examination of CD20 molecules by adding this antibody to reserch of CD20.
Protein A purified
Monoclonal