iFluor® 450 Anti-human CD42b Antibody *HIP1*

Catalogue Number: 10420041-AAT

Manufacturer:AAT Bioquest
Shelf Life:12 months
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 500 tests
Host name: Mouse
Clone: HIP1
Isotype: IgG1
Immunogen:
Application: FC, IF

Description

Description: HIP1 is an anti-human monoclonal antibody that targets the CD42b antigen. CD42b (sometimes called GP1BA or Glycocalicin) is a 145 kD single-pass type i membrane protein that is found on the surface of cells such as stem cells and platelets. CD42b is involved with important cellular pathways, for instance, the cell surface receptor signaling pathway and blood coagulation, intrinsic pathway. From a research standpoint, it is of biological interest due to its association with essential macromolecules/ligands such as von Willebrand factor (vWF), Thrombin, c and d. CD42b is a relatively rare antibody target, with fewer than 800 publications in the last decade. Even still, CD42b is vital to cell adhesion and cell biology research, typically serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to iFluor® 450 (ex/em = 451/502 nm). It is compatible with the 445 nm laser and 510/80 nm bandpass filter (for example, as in the BD FACSAria™ III).

Additional Text

Antibody Clonality

Monoclonal

Storage Note

See Protocol|12 months