CD3 PE-Cyanine7

Catalogue Number: 105386-CAP

Manufacturer:Caprico Biotechnologies
Preservative:0.09% Sodium azide
Ph:7.2
Physical state:Liquid
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Storage Condition:2-8°C
Unit(s): 200 Tests
Host name: Mouse
Clone: UCHT1
Isotype: IgG1, kappa
Immunogen: Human peripheral blood lymphocytes
Application: FC

Description

Description: The monoclonal UCHT1 clone recognizes CD3ε antigen, a 20KDa transmembrane cell-surface protein that belongs to the immunoglobulin superfamily. The CD3 complex contains a CD3γ chain, a CD3δ chain, and two CD3ε chains. These chains associate with a molecule known as the T-cell receptor (TCR) and the ζ-chain (zeta-chain) to generate an activation signal in T lymphocytes. CD3ε is expressed on T lymphocytes, NK-T cells, and to varying degrees on developing thymocytes. CD3 plays central roles in TCR signaling, T lymphocyte activation, and antigen recognition. Crosslinking of the TCR via plate bound UCHT1 monoclonal is widely used to study the activation T cell response in vitro.

Additional Text

Gene ID

916

Swiss-Prot

P07766

Accession Number

NM_000733.3

Concentration

50µg/mL

Protein Gene Name

CD3E

Antibody Clonality

Monoclonal

Price
319.00


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