iFluor® 790 Anti-human CD55 Antibody *HI55a*
Catalogue Number: 105500M1-AAT
| Manufacturer: | AAT Bioquest |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 500 tests |
| Host name: | Mouse |
| Clone: | HI55a |
| Isotype: | IgG2a |
| Immunogen: | |
| Application: | FC, IF |
Description
Description: HI55a is an anti-human monoclonal antibody that targets the CD55 antigen. CD55 (sometimes called Complement decay accelerating factor or DAF (Decay Accelerating Factor)) is a 60 - 70 kD single-pass type i membrane protein that is found on the surface of cells like macrophages, platelets, granulocytes, T cells and NK cells. CD55 is a component of vital cellular pathways, for example, the complement activation, classical pathway and regulation of lipopolysaccharide-mediated signaling pathway. Additionally, in some organisms, it is involved in the positive regulation of CD4-positive, alpha-beta T cell activation, upregulates CD4-positive, alpha-beta T cell proliferation and acts to positively regulate cytosolic calcium ion concentration. From a research standpoint, it is of biological interest due to its association with important macromolecules/ligands like SCR, CD97 and Echoviruses. CD55 is a fairly uncommon antibody target, with a little more than 3000 publications in the last decade. Even still, CD55 is typically used in flow cytometry applications as a phenotypic marker for differentiation of cell types, particularly in the study of cell biology, neuroinflammation and immunology. This antibody was purified through affinity chromatography and conjugated to iFluor® 790 (ex/em = 787/812 nm).
Additional Text
Antibody Clonality
Monoclonal
Storage Note
See Protocol|12 months
105500M1 Protocol
SUPPORT
outstanding technical support
PRODUCT
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DELIVERY
we offer free delivery to UK universities and non profit organisations