mFluor™ Red 780 Anti-human CD55 Antibody *HI55a*

mFluor™ Red 780 Anti-human CD55 Antibody HI55a

Catalogue Number: 105500W0-AAT

Manufacturer:	AAT Bioquest
Shelf Life:	12 months
Type:	Monoclonal Primary Antibody - Conjugated
Shipping Condition:	Blue Ice
Unit(s):	100 tests
Host name:	Mouse
Clone:	HI55a
Isotype:	IgG2a
Immunogen:
Application:	FC, IF

Overview
Datasheets

Description

Description: HI55a is an anti-human monoclonal antibody that targets the CD55 antigen. CD55 (sometimes called Complement decay accelerating factor or DAF (Decay Accelerating Factor)) is a 60 - 70 kD single-pass type i membrane protein that is found on the surface of cells like macrophages, platelets, granulocytes, T cells and NK cells. CD55 is a component of vital cellular pathways, for example, the complement activation, classical pathway and regulation of lipopolysaccharide-mediated signaling pathway. Additionally, in some organisms, it is involved in the positive regulation of CD4-positive, alpha-beta T cell activation, upregulates CD4-positive, alpha-beta T cell proliferation and acts to positively regulate cytosolic calcium ion concentration. From a research standpoint, it is of biological interest due to its association with important macromolecules/ligands like SCR, CD97 and Echoviruses. CD55 is a fairly uncommon antibody target, with a little more than 3000 publications in the last decade. Even still, CD55 is typically used in flow cytometry applications as a phenotypic marker for differentiation of cell types, particularly in the study of cell biology, neuroinflammation and immunology. This antibody was purified through affinity chromatography and conjugated to mFluor™ Red 780 (ex/em = 629/767 nm). It is compatible with the 633 nm laser and 780/60 nm bandpass filter (for example, as in the BD FACSCelesta™).

Additional Text

Antibody Clonality

Monoclonal

Storage Note

See Protocol|12 months

105500W0 Protocol

105500W0 MSDS

Price

£268.00

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