mFluor™ UV460 Anti-human CD58 Antibody *HI58a*
Catalogue Number: 105800Y0-AAT
| Manufacturer: | AAT Bioquest |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 tests |
| Host name: | Mouse |
| Clone: | HI58a |
| Isotype: | IgG1 |
| Immunogen: | |
| Application: | FC, IF |
Description
Description: HI58a is an anti-human monoclonal antibody that targets the CD58 antigen. CD58 (sometimes referred to as Lymphocyte function-associated antigen 3, LFA3 or LFA-3) is a 45 - 70 kD transmembrane protein that is located on the surface of cells such as macrophages, NK cells, dendritic cells, B cells and granulocytes. CD58 has been associated with key biological processes such as cell-cell adhesion, especially heterotypic cell-cell adhesion. Also, in certain organisms, it is involved in the positive regulation of interleukin-8 secretion. From a research standpoint, it is of biological interest due to its association with important macromolecules/ligands like CD2 and LFA-2. CD58 is a relatively rare antibody target, with less than 1000 publications in the last decade. Even still, CD58 is commonly used in flow cytometry applications as a phenotypic marker for differentiation of cell types, especially in the study of cell biology. This antibody was purified through affinity chromatography and conjugated to mFluor™ UV460 (ex/em = 358/456 nm). It is compatible with the 355 nm laser and 447/60 nm bandpass filter (for example, as in the Bio-Rad ZE5 Cell Analyzer).
Additional Text
Antibody Clonality
Monoclonal
Storage Note
See Protocol|12 months
105800Y0 Protocol
SUPPORT
outstanding technical support
PRODUCT
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DELIVERY
we offer free delivery to UK universities and non profit organisations