XFD700 Anti-human CD62p Antibody *HI62P*

Catalogue Number: 106221A0-AAT

Manufacturer:AAT Bioquest
Shelf Life:12 months
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 100 tests
Host name: Mouse
Clone: HI62P
Isotype: IgG1
Immunogen:
Application: FC, IF

Description

Description: HI62P is an anti-human monoclonal antibody that recognizes the CD62p antigen. CD62p (alternatively called SELP or PADGEM) is a 140 kD glycoprotein that is located on the surface of cells such as platelets. In some organisms, CD62p plays a role in the upregulation of phosphatidylinositol 3-kinase signaling and acts to positively regulate platelet activation. In addition, it has been associated with critical biological processes like leukocyte cell-cell adhesion, specifically calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules. From a research standpoint, it is of biological interest due to its association with important macromolecules/ligands such as CD24 and CD162. CD62p is a relatively rare antibody target, with fewer than 1000 publications in the last decade. Even still, CD62p is commonly used in flow cytometry applications as a phenotypic marker for differentiation of cell types, particularly in the study of immunology. This antibody was purified through affinity chromatography and conjugated to XFD700 (ex/em = 696/719 nm). XFD700 is manufactured by AAT Bioquest, and it has the same chemical structure of Alexa Fluor® 700 (Alexa Fluor® is the trademark of ThermoFisher).

Additional Text

Antibody Clonality

Monoclonal

Storage Note

See Protocol|12 months