Catalogue Number: 106221P0-AAT
| Manufacturer: | AAT Bioquest |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 25 tests |
| Host name: | Mouse |
| Clone: | HI62P |
| Isotype: | IgG1 |
| Immunogen: |
Description: HI62P is an anti-human monoclonal antibody that recognizes the CD62p antigen. CD62p (alternatively called SELP or PADGEM) is a 140 kD glycoprotein that is located on the surface of cells such as platelets. In some organisms, CD62p plays a role in the upregulation of phosphatidylinositol 3-kinase signaling and acts to positively regulate platelet activation. In addition, it has been associated with critical biological processes like leukocyte cell-cell adhesion, specifically calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules. From a research standpoint, it is of biological interest due to its association with important macromolecules/ligands such as CD24 and CD162. CD62p is a relatively rare antibody target, with fewer than 1000 publications in the last decade. Even still, CD62p is commonly used in flow cytometry applications as a phenotypic marker for differentiation of cell types, particularly in the study of immunology. This antibody was purified through affinity chromatography and conjugated to PE/XFD700 (ex/em = 566/721 nm). XFD700 is manufactured by AAT Bioquest, and it has the same chemical structure of Alexa Fluor® 700 (Alexa Fluor® is the trademark of ThermoFisher). It is compatible with the 561 nm laser and 695/40 nm bandpass filter (for example, as in the Agilent Technologies NovoCyte Advanteon).
Monoclonal
See Protocol|12 months