Catalogue Number: 106400A1-AAT
| Manufacturer: | AAT Bioquest |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 500 tests |
| Host name: | Mouse |
| Clone: | 10.1 |
| Isotype: | IgG1 |
| Immunogen: | |
| Application: | FC, IF |
Description: The 10.1 monoclonal antibody binds with human CD64, a 72 kD single-pass type i membrane protein typically expressed on the surface of granulocytes, monocytes and dendritic cells. In some organisms, CD64 enhances protein tyrosine kinase activity. Moreover, it is a member of vital cellular pathways, for example, the interferon-gamma-mediated signaling pathway and Fc-gamma receptor signaling pathway involved in phagocytosis. From a research standpoint, it is of biological interest due to its association with important macromolecules/ligands such as . CD64 is a fairly uncommon antibody target, with a little more than 4000 publications in the last decade. Even still, CD64 is often used in flow cytometry applications as a phenotypic marker for differentiation of cell types, particularly in the study of immunology and innate immunity. This antibody was purified through affinity chromatography and conjugated to iFluor® 560 (ex/em = 560/571 nm). It is compatible with the 561 nm laser and 577/35 nm bandpass filter (for example, as in the Luminex Amnis ImageStream).
Monoclonal
See Protocol|12 months