iFluor® 700 Anti-human CD85 Antibody *17G10.2*
Catalogue Number: 108500J0-AAT
| Manufacturer: | AAT Bioquest |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 tests |
| Host name: | Mouse |
| Clone: | 17G10.2 |
| Isotype: | IgG1, kappa |
| Immunogen: | |
| Application: | FC, IF |
Description
Description: The 17G10.2 monoclonal antibody binds to human CD85g, a single-pass type I membrane protein typically located on the surface of dendritic cells, neutrophils and eosinophils. CD85 plays a role in essential cellular pathways, in particular, the negative regulation of toll-like receptor 7 signaling pathway, negative regulation of toll-like receptor 9 signaling pathway and Fc-epsilon receptor signaling pathway. Moreover, in some organisms, it is a repressor of tumor necrosis factor production, is a negative regulator of toll-like receptor 9 signaling pathway and is involved in the negative regulation of interferon-alpha production. From a research standpoint, it is of biological interest due to its association with vital macromolecules/ligands. CD85 is a relatively rare antibody target, with fewer than 100 publications in the last decade. Even still, CD85g is typically used in flow cytometry applications as a phenotypic marker for differentiation of cell types, especially in the study of innate immunity and immunology. This antibody was purified through affinity chromatography and conjugated to iFluor® 700 (ex/em = 690/713 nm).
Additional Text
Antibody Clonality
Monoclonal
Storage Note
See Protocol|12 months
108500J0 Protocol
SUPPORT
outstanding technical support
PRODUCT
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DELIVERY
we offer free delivery to UK universities and non profit organisations