iFluor® 560 Anti-human CD85j Antibody *GHI/75*
Catalogue Number: 108510A1-AAT
| Manufacturer: | AAT Bioquest |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 500 tests |
| Host name: | Mouse |
| Clone: | GHI/75 |
| Isotype: | IgG2b, kappa |
| Immunogen: | |
| Application: | FC, IF |
Description
Description: The GHI/75 monoclonal antibody recognizes human CD85j, a 110 kD member of the ILT/LIR family commonly found on the surface of natural killer cells and T cells. CD85j plays a role in important cellular pathways, in particular, the Fc receptor mediated inhibitory signaling pathway and immune response-inhibiting cell surface receptor signaling pathway. Moreover, it has been closely linked to critical biological processes like response to virus, especially defense response to virus. In some organisms, CD85j is a negative regulator of transforming growth factor-beta secretion, represses natural killer cell mediated cytotoxicity and inhibits dendritic cell apoptotic process. From a research standpoint, it is of biological interest due to its association with critical macromolecules/ligands. CD85j is a relatively rare antibody target, with fewer than 300 publications in the last decade. Even still, CD85j is frequently used in flow cytometry applications as a phenotypic marker for differentiation of cell types, specifically in the study of immunology. This antibody was purified through affinity chromatography and conjugated to iFluor® 560 (ex/em = 560/571 nm). It is compatible with the 561 nm laser and 577/35 nm bandpass filter (for example, as in the Luminex Amnis FlowSight).
Additional Text
Antibody Clonality
Monoclonal
Storage Note
See Protocol|12 months
108510A1 Protocol
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations