Polyclonal Antibody to S1P3 receptor, Edg-3

Catalogue Number: 11-10017-ABO

Manufacturer:Abeomics
Type:Polyclonal Primary Antibody - Unconjugated
Alias:S1PR3||EDG3
Shipping Condition:Blue Ice
Storage Condition:2-8°C
Unit(s): 100 ug, 25 ug
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: A partial length recombinant S1P3 receptor, Edg-3 protein (amino acids 80-350) was used as the immunogen for this antibody.
Application: WB

Description

Description: S1PR3 (sphingosine-1phosphate receptor3) is a vascular barrier regulatory member of the S1P family of receptors (S1PR15) and a critical signaling molecule mediating cell proliferation, adhesion, angiogenesis, and vascular permeability. In a nitrated form protein in plasma it is found as a biomarker in patients with ALI (acute lung injury). S1PR3 plays an important role in promoting pulmonary inflammation, disrupting cell-cell junctions, and increasing lung permeability and alveolar flooding during inflammation.

Additional Text

Gene ID

1903

Gene Name

S1PR3

Uniprot ID

Q99500

Purification

Protein A purified

Antibody Clonality

Polyclonal

Application Notes

Western blot analysis: 2-4 µg/ml