Polyclonal Antibody to UBE1L2/MOP-4

Catalogue Number: 11-10018-ABO

Manufacturer:Abeomics
Type:Polyclonal Primary Antibody - Unconjugated
Alias:UBA6||MOP4||UBE1L2
Shipping Condition:Blue Ice
Storage Condition:2-8°C
Unit(s): 100 ug, 25 ug
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: A partial length recombinant UBE1L2 protein (amino acids 710-955) was used as the immunogen for this antibody.
Application: WB

Description

Description: Uba6/UBE1L2/MOP-4 is an ubiquitin-specific E1 type enzyme, homolog of the ubiquitin-activating enzyme, Uba1, which activates two ubiquitin-like proteins (UBLs), ubiquitin and FAT10. Some recent experiments suggest a testis-specific function of UBE1L2. UBE1L2 forms a thioester with FAT10 and this reaction requires the active-site cysteine of UBE1L2 and the C-terminal diglycine motif of FAT10. It can transfer ubiquitin to Ubc5 and Ubc13, suggesting its specialized role in ubiquitination reactions.

Additional Text

Gene Name

UBA6

Gene ID

55236

Uniprot ID

A0AVT1

Purification

Protein A purified

Antibody Clonality

Polyclonal

Application Notes

Western blot analysis: 2-4 µg/ml