Polyclonal Antibody to HOXA9
Catalogue Number: 11-12020-ABO
| Manufacturer: | Abeomics |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | HOXA9||HOX1G |
| Shipping Condition: | Blue Ice |
| Storage Condition: | 2-8°C |
| Unit(s): | 100 ug, 25 ug |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | A partial length recombinant HOXA9 protein (amino acids 63-272) was used as the immunogen for this antibody. |
| Application: | WB |
Description
Description: HOXA9 is a well-studied member of the HOXA cluster, and it plays a significant role in both normal hematopoiesis and leukemogenesis. HOXA9 is expressed in EC (Endothelial Cells) and its expression is rapidly downregulated during EC activation by inflammatory signals like TNF-alpha (Tumor Necrosis Factor-Alpha) and LPS (lipopolysaccharide) . In humans,HOXA9 was found to be highly expressed and required in some subtypes of leukemia, particularly mixed lineage leukemia (MLL)-rearranged leukemia. The aberrant overexpression of HOXA9 is thought to be associated with poor survival of acute myeloid leukemia (AML) patients.
Additional Text
Gene Name
Hoxa9
Uniprot ID
P31269
Gene ID
3205
Purification
Protein A purified
Antibody Clonality
Polyclonal
Application Notes
Western blot analysis: 1-2 µg/ml
11-12020 Datasheet
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