Polyclonal Antibody to NKX2-5
Catalogue Number: 11-12023-ABO
| Manufacturer: | Abeomics |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | NKX2-5||CSX||NKX2.5||NKX2E |
| Shipping Condition: | Blue Ice |
| Storage Condition: | 2-8°C |
| Unit(s): | 100 ug, 25 ug |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | A partial length recombinant NKX2-5 protein (amino acids 102-324) was used as the immunogen for this antibody. |
| Application: | WB |
Description
Description: Cardiac-specific Nkx2-5 is a member of the NK2 family of homeodomain-containing transcription factors, and its expression and functions overlap with those of GATA4, GATA5, and GATA6 during cardiovascular genesis, especially in the regulation of target gene expression synergistically with GATA4, which justifies screening for Nkx2-5 as a prime candidate gene for idiopathic AF (Atrial Fibrillation). NKX2-5 plays an important role in heart formation and development. Moreover, NKX2-5 not only individually acts in transcriptional regulation, but also interacts with other transcription factors in the early stage of cardiac development.
Additional Text
Gene Name
NKX2-5
Uniprot ID
P52952
Gene ID
1482
Purification
Protein A purified
Antibody Clonality
Polyclonal
Application Notes
Western blot analysis: 2-4 µg/ml
11-12023 Datasheet
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