Polyclonal Antibody to UNC93B

Catalogue Number: 11-3004-ABO

Manufacturer:Abeomics
Type:Polyclonal Primary Antibody - Unconjugated
Alias:UNC93B1||UNC93||UNC93B
Shipping Condition:Blue Ice
Storage Condition:2-8°C
Unit(s): 100 ug, 25 ug
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: A partial length recombinant UNC93B protein (amino acids 300-597) was used as the immunogen for this antibody.
Application: WB

Description

Description: Unc-93 homolog B1 (C. elegans), also known as UNC93B1, is a protein which in humans is encoded by the UNC93B1 gene. Plays an important role in innate and adaptive immunity by regulating nucleotide-sensing Toll-like receptor (TLR) signaling also they helps in transportation of TLRs (basically TLR7 and TLR9) from endoplasmic reticulum to endolysosomes. Diseases associated with UNC93B1 include herpes simplex encephalitis 1, and herpes simplex encephalitis. It is expressed in plasmocytoid dendritic cells (at protein level),antigen-presenting cells(high) and at lower level in kidney.

Additional Text

Gene Name

UNC93B1

Uniprot ID

Q9H1C4

Gene ID

81622

Purification

Protein A purified

Antibody Clonality

Polyclonal

Application Notes

Western blot analysis: 4-6 µg/ml