Polyclonal Antibody to Viperin
Catalogue Number: 11-3030-ABO
| Manufacturer: | Abeomics |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | RSAD2||CIG5 |
| Shipping Condition: | Blue Ice |
| Storage Condition: | 2-8°C |
| Unit(s): | 100 ug, 25 ug |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | A partial length recombinant Viperin protein (amino acids 100-330) was used as the immunogen for this antibody. |
| Application: | WB |
Description
Description: Radical S-adenosyl methionine domain-containing protein 2 is commonly known as Viperin consisting of 43 kDa protein. which is a interferon inducible viral protein. Viperin expression is induced by IFNI+/-, IFNb, IFNg, human cytomegalovirus (HCMV) envelope protein, glycoprotein B (gB), etc. Viperin interaction with the viral protein vMIA results in viperin relocalization from the endoplasmic reticulum to the mitochondria. It interacts with the mitochondrial trifunctional protein which mediates beta-oxidation of fatty acids to generate ATP. Viperin promotes TLR7 and TLR9-dependent production of IFN-beta and also plays an important role in CD4+ T-cell activation and differentiation. Viperin is highly expressed in mouse and human brain.
Additional Text
Gene Name
RSAD2
Gene ID
91543
Uniprot ID
Q8WXG1
Purification
Protein A purified
Antibody Clonality
Polyclonal
Application Notes
Western blot analysis: 3-5 µg/ml
11-3030 Datasheet
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