Polyclonal Antibody to Mouse TLR4
Catalogue Number: 11-3039-ABO
| Manufacturer: | Abeomics |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | Toll-like receptor 4, CD284 |
| Shipping Condition: | Blue Ice |
| Storage Condition: | 2-8°C |
| Unit(s): | 100 ug, 25 ug |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | A partial length recombinant m TLR4 protein (amino acids 400-650) was used as the immunogen for this antibody. |
| Application: | WB |
Description
Description: TLR4 (Toll-like receptor-4) is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. It primarily mediates cellular signaling induced by Gram negative bacteria. TLR4 is highly specific for LPS and it is associated with CD14, a co-receptor for LPS. The downstream signaling pathway of TLR4 leads to the activation of NF-kappaB through myeloid differentiation protein (MyD88) and IL-1 receptor-associated kinase in various cell types.
Additional Text
Gene Name
TLR4
Gene ID
21898
Purification
Protein A purified
Uniprot ID
Q9QUK6
Antibody Clonality
Polyclonal
Application Notes
Western blot analysis: 1-2 µg/ml
11-3039 Datasheet
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