Polyclonal Antibody to TLR1
Catalogue Number: 11-3041-ABO
| Manufacturer: | Abeomics |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | TLR1||KIAA0012 |
| Shipping Condition: | Blue Ice |
| Storage Condition: | 2-8°C |
| Unit(s): | 100 ug, 25 ug |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | A partial length recombinant TLR1 protein (amino acids 300-500) was used as the immunogen for this antibody. |
| Application: | WB |
Description
Description: Toll/interleukin-1 receptor-like protein (TLR1) is a member of the Toll-like receptor (TLR) family, which has close similarity to Drosophila Toll homologs. Toll receptors are involved in mediating dorsoventral polarization in the developing Drosophila embryo. TLR1 is a type I transmembrane receptor that characteristically contains an extracellular domain consisting of several leucine-rich regions along with a single cytoplasmic Toll/IL-1R-like domain. TLRs generally exist as homodimers, but TLR6 forms heterodimers with TLR2 and binds lipopeptide components of gram-positive and gram-negative bacterial cell walls. TLR1 is found to be involved in ocular toxoplasmosis and leprosy. It is highly expressed in spleen, ovary, peripheral blood leukocytes, thymus, and small intestine.
Additional Text
Gene Name
TLR1
Gene ID
7096
Uniprot ID
Q15399
Purification
Protein A purified
Antibody Clonality
Polyclonal
Application Notes
Western blot analysis: 4-6 µg/ml
11-3041 Datasheet
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