Polyclonal Antibody to CUEDC2
Catalogue Number: 11-6003-ABO
| Manufacturer: | Abeomics |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | CUEDC2||C10orf66||HOYS6 |
| Shipping Condition: | Blue Ice |
| Storage Condition: | 2-8°C |
| Unit(s): | 100 ug, 25 ug |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | A partial length recombinant CUEDC2 protein (amino acids 100-280) was used as the immunogen for this antibody. |
| Application: | WB |
Description
Description: CUE domain-containing protein 2 commonly known as CUEDC2 is a 32 kDa protein having CUE Domain. It is involved in ubiquitin and proteasome-mediated degradation of progesterone receptor and estrogen receptor. It interacts with PRB isoform of progesterone receptor (PR) and modulates estrogen receptor (ER)-alpha protein stability through the ubiquitin-proteasome pathway. High level expression of CUEDC2 found in breast cancer tissue compared to normal adjacent tissue. It is found that CUEDC2 has some role in regulating IKK dephosphorylation by recruiting PP1.
Additional Text
Gene Name
CUEDC2
Gene ID
79004
Purification
Protein A purified
Uniprot ID
Q9H467
Antibody Clonality
Polyclonal
Application Notes
Western blot analysis: 1-2 µg/ml
11-6003 Datasheet
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