Polyclonal Antibody to HOIL-1L/RBCK1
Catalogue Number: 11-6007-ABO
| Manufacturer: | Abeomics |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | RBCK1||C20orf18||RNF54||UBCE7IP3||XAP3||XAP4 |
| Shipping Condition: | Blue Ice |
| Storage Condition: | 2-8°C |
| Unit(s): | 100 ug, 25 ug |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | A partial length recombinant HOIL-1L/RBCK1 protein (amino acids 121-333) was used as the immunogen for this antibody. |
| Application: | WB |
Description
Description: RBCK1 (RanBP-type and C3HC4-type zinc finger containing 1) is a transcription factor belonging to the RING-IBR protein family. It shuttles between the nucleus and cytoplasm, possessing both the nuclear export and localization signals within its amino acid sequence. RBCK1 deficiency causes polyglucosan storage myopathy associated with progressive muscle weakness and cardiomyopathy. RBCK1 negatively regulates the cellular antiviral response. RBCK1 regulates cell cycle progression and proliferation of ERalpha (estrogen receptor alpha)-positive breast cancer cells by supporting transcription of ERalpha and cyclin B1.
Additional Text
Gene Name
RBCK1
Uniprot ID
Q9BYM8
Gene ID
10616
Purification
Protein A purified
Antibody Clonality
Polyclonal
Application Notes
Western blot analysis: 2-4 µg/ml
11-6007 Datasheet
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