iFluor® 560 Anti-human CD107 Antibody *H4B4*
Catalogue Number: 110710A0-AAT
| Manufacturer: | AAT Bioquest |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 tests |
| Host name: | Mouse |
| Clone: | H4B4 |
| Isotype: | IgG1, kappa |
| Immunogen: | |
| Application: | FC, IF |
Description
Description: H4B4 is an anti-human monoclonal antibody that targets the CD107b antigen. CD107b (sometimes called LAMP2 or LAMPb) is a 45 kD transmembrane protein that is found on the surface of cells like granulocytes and endothelial cells. In many organisms, CD107 is a suppressor of protein-containing complex assembly. Additionally, it has been associated with essential biological processes like chaperone-mediated autophagy, particularly protein targeting to lysosome involved in chaperone-mediated autophagy. From a research standpoint, it is of biological interest due to its association with vital macromolecules/ligands. CD107 is a relatively rare antibody target, with fewer than 800 publications in the last decade. Even still, CD107b is typically used in flow cytometry applications as a phenotypic marker for differentiation of cell types, specifically in the study of protein trafficking and clearance and neuroscience. This antibody was purified through affinity chromatography and conjugated to iFluor® 560 (ex/em = 560/571 nm). It is compatible with the 561 nm laser and 586/15 nm bandpass filter (for example, as in the BD FACSCelesta™).
Additional Text
Antibody Clonality
Monoclonal
Storage Note
See Protocol|12 months
110710A0 Protocol
SUPPORT
outstanding technical support
PRODUCT
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DELIVERY
we offer free delivery to UK universities and non profit organisations