iFluor® 700 Anti-human CD109 Antibody *W7C5*

Catalogue Number: 110900J1-AAT

Manufacturer:AAT Bioquest
Shelf Life:12 months
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 500 tests
Host name: Mouse
Clone: W7C5
Isotype: IgG1
Immunogen:
Application: FC, IF

Description

Description: The W7C5 monoclonal antibody binds with human CD109, a 162 kD transmembrane protein typically expressed on the surface of T cells and T cell lines. CD109 acts in essential cellular pathways, for instance, the negative regulation of transforming growth factor beta receptor signaling pathway. Additionally, in some organisms, it is a suppressor of transforming growth factor beta receptor signaling pathway, is a repressor of wound healing and is a repressor of keratinocyte proliferation. From a research standpoint, it is of biological interest due to its association with critical macromolecules/ligands. CD109 is a relatively rare antibody target, with fewer than 600 publications in the last decade. Even still, CD109 is vital to immunology research, frequently serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to iFluor® 700 (ex/em = 690/713 nm).

Additional Text

Antibody Clonality

Monoclonal

Storage Note

See Protocol|12 months