Catalogue Number: 110900J1-AAT
| Manufacturer: | AAT Bioquest |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 500 tests |
| Host name: | Mouse |
| Clone: | W7C5 |
| Isotype: | IgG1 |
| Immunogen: | |
| Application: | FC, IF |
Description: The W7C5 monoclonal antibody binds with human CD109, a 162 kD transmembrane protein typically expressed on the surface of T cells and T cell lines. CD109 acts in essential cellular pathways, for instance, the negative regulation of transforming growth factor beta receptor signaling pathway. Additionally, in some organisms, it is a suppressor of transforming growth factor beta receptor signaling pathway, is a repressor of wound healing and is a repressor of keratinocyte proliferation. From a research standpoint, it is of biological interest due to its association with critical macromolecules/ligands. CD109 is a relatively rare antibody target, with fewer than 600 publications in the last decade. Even still, CD109 is vital to immunology research, frequently serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to iFluor® 700 (ex/em = 690/713 nm).
Monoclonal
See Protocol|12 months