mFluor™ Violet 540 Anti-human CD109 Antibody *W7C5*
Catalogue Number: 11090121-AAT
| Manufacturer: | AAT Bioquest |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 500 tests |
| Host name: | Mouse |
| Clone: | W7C5 |
| Isotype: | IgG1 |
| Immunogen: | |
| Application: | FC, IF |
Description
Description: The W7C5 monoclonal antibody binds with human CD109, a 162 kD transmembrane protein typically expressed on the surface of T cells and T cell lines. CD109 acts in essential cellular pathways, for instance, the negative regulation of transforming growth factor beta receptor signaling pathway. Additionally, in some organisms, it is a suppressor of transforming growth factor beta receptor signaling pathway, is a repressor of wound healing and is a repressor of keratinocyte proliferation. From a research standpoint, it is of biological interest due to its association with critical macromolecules/ligands. CD109 is a relatively rare antibody target, with fewer than 600 publications in the last decade. Even still, CD109 is vital to immunology research, frequently serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to mFluor™ Violet 540 (ex/em = 394/537 nm). It is compatible with the 405 nm laser and 510/50 nm bandpass filter (for example, as in the BD FACSCanto™ II).
Additional Text
Antibody Clonality
Monoclonal
Storage Note
See Protocol|12 months
11090121 Protocol
SUPPORT
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PRODUCT
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DELIVERY
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