APC/XFD750 Anti-human CD114 Antibody *LMM741*

Catalogue Number: 111401D1-AAT

Manufacturer:AAT Bioquest
Shelf Life:12 months
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 100 tests
Host name: Mouse
Clone: LMM741
Isotype: IgG1, kappa
Immunogen:

Description

Description: The LMM741 monoclonal antibody binds to human CD114, a 130 kD single-pass type I membrane protein typically found on the surface of endothelial cells, platelets, myeloid progenitor cells, neutrophils and granulocytes. CD114 acts in key cellular pathways, in particular, the cytokine-mediated signaling pathway. From a research standpoint, it is of biological interest due to its association with key macromolecules/ligands such as jak2, jak1 and G-CSF. CD114 is a relatively rare antibody target, with fewer than 100 publications in the last decade. Even still, CD114 is essential for immunology research, commonly serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to APC/XFD750 (ex/em = 756/785 nm). XFD750 is manufactured by AAT Bioquest, and it has the same chemical structure of Alexa Fluor® 750 (Alexa Fluor® is the trademark of ThermoFisher).

Additional Text

Antibody Clonality

Monoclonal

Storage Note

See Protocol|12 months