PE/XFD700 Anti-human CD114 Antibody *LMM741*
Catalogue Number: 111401O1-AAT
| Manufacturer: | AAT Bioquest |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 tests |
| Host name: | Mouse |
| Clone: | LMM741 |
| Isotype: | IgG1, kappa |
| Immunogen: |
Description
Description: The LMM741 monoclonal antibody binds to human CD114, a 130 kD single-pass type I membrane protein typically found on the surface of endothelial cells, platelets, myeloid progenitor cells, neutrophils and granulocytes. CD114 acts in key cellular pathways, in particular, the cytokine-mediated signaling pathway. From a research standpoint, it is of biological interest due to its association with key macromolecules/ligands such as jak2, jak1 and G-CSF. CD114 is a relatively rare antibody target, with fewer than 100 publications in the last decade. Even still, CD114 is essential for immunology research, commonly serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to PE/XFD700 (ex/em = 566/721 nm). XFD700 is manufactured by AAT Bioquest, and it has the same chemical structure of Alexa Fluor® 700 (Alexa Fluor® is the trademark of ThermoFisher). It is compatible with the 561 nm laser and 710/50 nm bandpass filter (for example, as in the BD Special Order LSRFortessa™ Cell Analyzer).
Additional Text
Antibody Clonality
Monoclonal
Storage Note
See Protocol|12 months
111401O1 MSDS
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