XFD700 Anti-human CD123 Antibody *12H7*
Catalogue Number: 11231190-AAT
| Manufacturer: | AAT Bioquest |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 tests |
| Host name: | Mouse |
| Clone: | 12H7 |
| Isotype: | IgG1, kappa |
| Immunogen: | |
| Application: | FC, IF |
Description
Description: The 12H7 monoclonal antibody binds to human CD123, a 70 kD single-pass type I membrane protein often located on the surface of macrophages, hematopoietic progenitors and dendritic cells. CD123 acts in vital cellular pathways, for instance, the cytokine-mediated signaling pathway. From a research standpoint, it is of biological interest due to its association with essential macromolecules/ligands like CD131. CD123 is a fairly uncommon antibody target, with a little more than 3900 publications in the last decade. Even still, CD123 is essential for immunology research, typically serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to XFD700 (ex/em = 696/719 nm). XFD700 is manufactured by AAT Bioquest, and it has the same chemical structure of Alexa Fluor® 700 (Alexa Fluor® is the trademark of ThermoFisher).
Additional Text
Antibody Clonality
Monoclonal
Storage Note
See Protocol|12 months
11231190 Protocol
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