Catalogue Number: 113201C0-AAT
| Manufacturer: | AAT Bioquest |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 25 tests |
| Host name: | Rat |
| Clone: | TUGh4 |
| Isotype: | IgG2b, kappa |
| Immunogen: |
Description: The TUGh4 monoclonal antibody binds to human/ dog CD132, a 64 - 70 kD member of the Ig superfamily frequently located on the surface of macrophages and B cells. CD132 is a component of important cellular pathways, namely, the interleukin-21-mediated signaling pathway, interleukin-9-mediated signaling pathway and interleukin-2-mediated signaling pathway. In addition, in certain organisms, it is an enhancer of phagocytosis. From a research standpoint, it is of biological interest due to its association with important macromolecules/ligands such as CD124, JAK1, CD25 and lck. CD132 is a relatively rare antibody target, with fewer than 800 publications in the last decade. Even still, CD132 has a variety of applications in immunology research, frequently serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to APC/Cy7 (ex/em = 754/779 nm).
Monoclonal
See Protocol|12 months