iFluor® 560 Anti-human/ non-human primates CD137 Antibody *4B4-1*
Catalogue Number: 113700A1-AAT
| Manufacturer: | AAT Bioquest |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 500 tests |
| Host name: | Mouse |
| Clone: | 4B4-1 |
| Isotype: | IgG1, kappa |
| Immunogen: | |
| Application: | FC, IF |
Description
Description: The 4B4-1 monoclonal antibody reacts with human/ non-human primates CD137, a 30 kD member of the TNFR superfamily frequently located on the surface of T cells and follicular dendritic cells. CD137 acts in vital cellular pathways, for example, the tumor necrosis factor-mediated signaling pathway. In addition, in certain organisms, it downregulates cell population proliferation. From a research standpoint, it is of biological interest due to its association with essential macromolecules/ligands such as 4-1BB ligand. CD137 is a fairly uncommon antibody target, with a little more than 4100 publications in the last decade. Even still, CD137 is often used in flow cytometry applications as a phenotypic marker for differentiation of cell types, specifically in the study of immunology and costimulatory molecules. This antibody was purified through affinity chromatography and conjugated to iFluor® 560 (ex/em = 560/571 nm). It is compatible with the 561 nm laser and 586/15 nm bandpass filter (for example, as in the BD FACSCelesta™).
Additional Text
Antibody Clonality
Monoclonal
Storage Note
See Protocol|12 months
113700A1 Protocol
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations