Catalogue Number: 11380121-AAT
| Manufacturer: | AAT Bioquest |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 500 tests |
| Host name: | Mouse |
| Clone: | MI15 |
| Isotype: | IgG1 |
| Immunogen: | |
| Application: | FC, IF |
Description: The MI15 monoclonal antibody reacts with human CD138, a 100 - 200 kD transmembrane protein typically expressed on the surface of b cells, plasma cells, epithelial cells and endothelial cells. CD138 is involved with important cellular pathways, in particular, the cytokine-mediated signaling pathway and canonical Wnt signaling pathway. Also, in certain organisms, it enhances extracellular exosome assembly and is a promoter of exosomal secretion. From a research standpoint, it is of biological interest due to its association with critical macromolecules/ligands such as Fibronectin. CD138 is a fairly uncommon antibody target, with a little more than 7000 publications in the last decade. Even still, CD138 is frequently used in flow cytometry applications as a phenotypic marker for differentiation of cell types, specifically in the study of cell motility/cytoskeleton/structure, cell biology and synaptic biology. This antibody was purified through affinity chromatography and conjugated to mFluor™ Violet 540 (ex/em = 394/537 nm). It is compatible with the 405 nm laser and 525/50 nm bandpass filter (for example, as in the Bio-Rad ZE5 Cell Analyzer).
Monoclonal
See Protocol|12 months