Catalogue Number: 114601O0-AAT
| Manufacturer: | AAT Bioquest |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 25 tests |
| Host name: | Mouse |
| Clone: | P1H12 |
| Isotype: | IgG1 |
| Immunogen: |
Description: P1H12 is an anti-rabbit/ dog/ mouse/ human monoclonal antibody that recognizes the CD146 antigen. CD146 (also known as MCAM) is a 118 kD member of the Ig superfamily that is expressed on the surface of cells such as T cells and endothelial cells. In some organisms, CD146 is involved in the positive regulation of cell migration, and is associated with a variety of biologically interesting macromolecules/ligands. CD146 is a fairly uncommon antibody target, with a little more than 4300 publications in the last decade. Even still, CD146 is often used in flow cytometry applications as a phenotypic marker for differentiation of cell types, specifically in the study of stem cells and innate immunity. This antibody was purified through affinity chromatography and conjugated to PE/XFD700 (ex/em = 566/721 nm). XFD700 is manufactured by AAT Bioquest, and it has the same chemical structure of Alexa Fluor® 700 (Alexa Fluor® is the trademark of ThermoFisher). It is compatible with the 561 nm laser and 695/40 nm bandpass filter (for example, as in the Agilent Technologies NovoCyte).
Monoclonal
See Protocol|12 months