Catalogue Number: 11470031-AAT
| Manufacturer: | AAT Bioquest |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 500 tests |
| Host name: | Mouse |
| Clone: | MEM-M6/6 |
| Isotype: | IgG1 |
| Immunogen: | |
| Application: | FC, IF |
Description: The MEM-M6/6 monoclonal antibody binds to human CD147, a 55 - 65 kD member of the Ig superfamily often expressed on the surface of endothelial cells and leukocytes. In certain organisms, CD147 acts to positively regulate interleukin-6 production. Moreover, it is a component of key cellular pathways, for example, the cell surface receptor signaling pathway. From a research standpoint, it is of biological interest due to its association with essential macromolecules/ligands. CD147 is a fairly uncommon antibody target, with a little more than 3200 publications in the last decade. Even still, CD147 has been widely used in cell adhesion and immunology research, typically serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to iFluor® 430 (ex/em = 433/498 nm). It is compatible with the 445 nm laser and 510/80 nm bandpass filter (for example, as in the BD FACSAria™ Fusion).
Monoclonal
See Protocol|12 months